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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC16
All Species:
22.12
Human Site:
S586
Identified Species:
32.44
UniProt:
Q13042
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13042
NP_001072113.1
620
71656
S586
G
L
T
P
L
E
T
S
R
K
T
P
D
S
R
Chimpanzee
Pan troglodytes
XP_001141335
657
75449
S623
G
L
T
P
L
E
T
S
R
K
T
P
D
S
R
Rhesus Macaque
Macaca mulatta
XP_001089625
620
71585
S586
G
L
T
P
L
E
T
S
R
K
T
P
D
S
R
Dog
Lupus familis
XP_848577
620
71476
S586
G
L
V
P
L
E
T
S
R
K
T
P
D
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R349
620
71442
S586
G
L
A
P
L
Q
N
S
T
K
A
P
E
S
R
Rat
Rattus norvegicus
NP_001019915
620
71343
A586
G
L
A
P
L
E
N
A
T
K
T
P
E
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513048
324
37070
R291
L
E
T
S
H
P
T
R
K
A
A
D
P
R
P
Chicken
Gallus gallus
NP_001006265
624
72618
S588
S
I
V
T
L
E
T
S
H
Q
R
T
N
T
D
Frog
Xenopus laevis
NP_001087093
621
71792
S584
G
I
M
A
L
E
T
S
N
L
L
P
K
S
S
Zebra Danio
Brachydanio rerio
NP_001032466
616
70436
N583
C
I
E
T
P
S
F
N
A
D
K
Q
T
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623316
640
73022
E597
N
L
F
S
G
W
G
E
S
S
N
K
A
D
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203133
551
62760
N348
L
E
Y
G
L
T
K
N
F
K
L
A
D
K
F
Poplar Tree
Populus trichocarpa
XP_002331799
542
62607
A509
A
Y
T
Y
H
L
Q
A
L
W
L
K
P
D
D
Maize
Zea mays
NP_001141501
580
66070
Y546
F
E
A
A
I
N
Y
Y
H
K
A
L
W
L
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565188
543
61743
A510
A
I
S
Y
Y
H
K
A
L
W
L
K
P
D
D
Baker's Yeast
Sacchar. cerevisiae
P09798
840
94974
R800
D
P
V
N
M
A
K
R
L
R
T
Q
K
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
99.3
97.9
N.A.
95.4
95.9
N.A.
48.2
91.5
88.8
79.1
N.A.
N.A.
49.6
N.A.
49
Protein Similarity:
100
94.3
99.6
98.5
N.A.
97.9
98
N.A.
50.1
95.8
95.8
87.9
N.A.
N.A.
68.1
N.A.
66.7
P-Site Identity:
100
100
100
86.6
N.A.
60
66.6
N.A.
13.3
26.6
46.6
0
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
80
N.A.
20
53.3
53.3
13.3
N.A.
N.A.
6.6
N.A.
26.6
Percent
Protein Identity:
35.8
36.9
N.A.
38.2
23.8
N.A.
Protein Similarity:
52.1
54.6
N.A.
54.3
41.5
N.A.
P-Site Identity:
6.6
6.6
N.A.
0
6.6
N.A.
P-Site Similarity:
13.3
20
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
19
13
0
7
0
19
7
7
19
7
7
0
7
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
7
0
7
32
25
25
% D
% Glu:
0
19
7
0
0
44
0
7
0
0
0
0
13
7
0
% E
% Phe:
7
0
7
0
0
0
7
0
7
0
0
0
0
0
7
% F
% Gly:
44
0
0
7
7
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
13
7
0
0
13
0
0
0
0
0
0
% H
% Ile:
0
25
0
0
7
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
0
0
0
0
0
19
0
7
50
7
19
13
7
7
% K
% Leu:
13
44
0
0
57
7
0
0
19
7
25
7
0
7
0
% L
% Met:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
7
0
7
13
13
7
0
7
0
7
0
0
% N
% Pro:
0
7
0
38
7
7
0
0
0
0
0
44
19
7
7
% P
% Gln:
0
0
0
0
0
7
7
0
0
7
0
13
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
13
25
7
7
0
0
7
38
% R
% Ser:
7
0
7
13
0
7
0
44
7
7
0
0
0
38
7
% S
% Thr:
0
0
32
13
0
7
44
0
13
0
38
7
7
7
0
% T
% Val:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
13
0
0
7
0
0
% W
% Tyr:
0
7
7
13
7
0
7
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _